|
KMID : 0381219850170020083
|
|
Journal of RIMSK
1985 Volume.17 No. 2 p.83 ~ p.90
|
|
|
The Endocrinology of Pregnancy
|
|
|
|
|
Abstract
|
|
|
During human pregnancy, the placenta synthesizes large quantities of progesterone, estradiol, estrone, and estriol and secretes these steroid hormones into both the maternal and fetal circulations.
Even so, the placenta never becomes an autonomous endocrine organ. The steroids produced by the placenta are instead derived to it via the maternal and fetal streams.; progesterone from maternal cholesterol, estradiol and estrone from maternal and fetal dehydroepiandrosterone sulfate, and estriol largely from fetal 16a-hydroxy dehydroepiandrosterone sulfate.
And the placenta has been recognized as a source of pregnancy-specific proteins such as human chorionic gonadotropin, human chorionic somatotropin or human placental lactogen, human chorionic thyrotropin, human chorionic ACTH, LHRH and somatostatin etc.
These protein hormones are composed of polypepties chains which of resemble pituitary hormones in their biologic function and amino acid composition.
This article will review the knowledge about formation and metabolism of steroid hormones in pregnancy and the proposed functions of these hormones: and the formation of protein hormones of placenta and their regulatory roles in pregnancy.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|